Efficacy of the combination of Tenghuangjiangu tablets, alfacalcidol capsules and caltrate D3 tablets in osteoporotic vertebral compression fracture, and their effects on bone metabolic indices

نویسندگان

چکیده

Purpose: To investigate the efficacy of combination Tenghuangjiangu tablets, Alfacalcidol capsules and Caltrate D3 tablets in osteoporotic vertebral compression fracture (OVCF) their effects on bone metabolic indices. 
 Methods: Ninety-six patients with OVCF were randomly categorized into study group (SG) control (CG). Patients CG orally took while those SG given addition to caltrate tablets. The Bone mineral density (BMD) values treatment compared. levels metabolism markers (PINP, β-CTX, BGP, NBAP), CT PTH determined using electrochemiluminescence immunoassay, Ca2+ assessed liquid level detection. incidence adverse reactions (re-fracture, gastrointestinal reaction, hypotension abnormal coagulation function) Results: Treatment was 91.67 %, which significantly higher than that (81.25 %; p < 0.05). Before treatment, two groups showed no significant differences BMD, PINP, NBAP, Ca2+, CT, (p > After exhibited levels, lower β-CTX a rate Conclusion: capsules, improves indices, reducing reactions.

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ژورنال

عنوان ژورنال: Tropical Journal of Pharmaceutical Research

سال: 2022

ISSN: ['1596-5996', '1596-9827']

DOI: https://doi.org/10.4314/tjpr.v21i10.19